Negative cofitness for PP_4740 from Pseudomonas putida KT2440

Type I restriction enzyme EcoAI R protein
SEED: Type I restriction-modification system, restriction subunit R (EC 3.1.21.3)
KEGG: type I restriction enzyme, R subunit

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	PP_0513		DNA-binding transcriptional repressor NrdR-Zn2+-ATP/dATP	-0.19
2	PP_3201		BNR domain protein	-0.16
3	PP_4319		conserved exported protein of unknown function	-0.16
4	PP_3072		Ecotin	-0.16
5	PP_5095		pyrroline-5-carboxylate reductase	-0.16
6	PP_4832		Precorrin-6x reductase	-0.15
7	PP_2328		Phosphoadenosine phosphosulfate reductase	-0.15
8	PP_1088		Argininosuccinate synthase	-0.15
9	PP_2375		cobalamin-dependent methionine synthase	-0.15
10	PP_5035		Histidine utilization repressor	-0.15
11	PP_4243		non-ribosomal peptide synthase (subunit of ferribactin synthase)	-0.15
12	PP_4695		Sensory box histidine kinase	-0.15
13	PP_5609		conserved protein of unknown function	-0.15
14	PP_1233		sulfurtransferase	-0.14
15	PP_2914		osmosensory proline/betaine/H+ permease	-0.14
16	PP_4219		non-ribosomal peptide synthetase	-0.14
17	PP_2818		Multidrug efflux RND transporter MexD	-0.14
18	PP_1676		subunit of adenosylcobinamide-phosphate synthase beta component	-0.14
19	PP_4782		Phosphomethylpyrimidine kinase	-0.14
20	PP_1995		N-(5'-phosphoribosyl)anthranilate isomerase	-0.14

Or look for positive cofitness