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  • Negative cofitness for PP_4734 from Pseudomonas putida KT2440

    DNA-binding transcriptional dual regulator, LldR-L-lactate
    SEED: Lactate-responsive regulator LldR in Enterobacteria, GntR family
    KEGG: GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex

    Computing cofitness values with 989 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 PP_0951 Ribosome hibernation promoting factor -0.30
    2 PP_2436 Transcriptional regulator, LysR family -0.29
    3 PP_4948 Acyl-CoA dehydrogenase family protein -0.28
    4 PP_3925 conserved protein of unknown function -0.28
    5 PP_5502 ribosome modulation factor -0.28
    6 PP_0697 ribosomal-protein-S18-alanine N-acetyltransferase -0.26
    7 PP_2862 Undecaprenyl-diphosphatase -0.26
    8 PP_1351 putative 2-dehydropantoate 2-reductase -0.25
    9 PP_3833 Response regulator -0.24
    10 PP_4545 beta-ketodecanoyl-(Acyl-carrier-protein) synthase -0.24
    11 PP_1319 Ubiquinol--cytochrome c reductase, cytochrome c1 -0.24
    12 PP_0767 Transcriptional regulator, LuxR family -0.23
    13 PP_0494 selenocysteyl-tRNA-specific translation elongation factor -0.23
    14 PP_4342 flagellar synthesis regulator, putative ATPase -0.23
    15 PP_1318 Cytochrome b -0.23
    16 PP_1328 Protein MraZ -0.23
    17 PP_4722 Transcription elongation factor GreA -0.23
    18 PP_3923 Phosphoglycerate mutase -0.22
    19 PP_0489 formate dehydrogenase-O major subunit -0.22
    20 PP_0823 Selenide, water dikinase -0.22

    Or look for positive cofitness