Negative cofitness for PP_4699 from Pseudomonas putida KT2440

3-methyl-2-oxobutanoate hydroxymethyltransferase
SEED: 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11)
KEGG: 3-methyl-2-oxobutanoate hydroxymethyltransferase

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	PP_5283		periplasmic dipeptide transport protein	-0.33
2	PP_5053		Protein-export protein SecB	-0.32
3	PP_1113		Pyridoxal-phosphate dependent enzyme family protein	-0.30
4	PP_2437		putative Acyl-CoA dehydrogenase	-0.27
5	PP_2387		conserved protein of unknown function	-0.27
6	PP_2372		putative Periplasmic sugar-binding protein	-0.26
7	PP_4171		conserved exported protein of unknown function	-0.26
8	PP_0163		putative transcriptional regulator	-0.26
9	PP_5200		proline aminopeptidase P II	-0.26
10	PP_1279		Probable alginate O-acetylase AlgJ	-0.26
11	PP_2148		transcription-repair coupling factor	-0.25
12	PP_1523		conserved protein of unknown function	-0.25
13	PP_2413		GGDEF family protein	-0.25
14	PP_4872		putative enzyme of unknown function	-0.25
15	PP_1909		putative septum formation protein	-0.24
16	PP_1807		2-dehydro-3-deoxyphosphooctonate aldolase	-0.24
17	PP_0355		Response regulator	-0.24
18	PP_5101		coproporphyrinogen/heterocyclic compound oxidase (aerobic)	-0.24
19	PP_2361		putative chaperone protein	-0.24
20	PP_3769		conserved exported protein of unknown function	-0.24

Or look for positive cofitness