Negative cofitness for PP_4680 from Pseudomonas putida KT2440

acetohydroxybutanoate synthase / acetolactate synthase
SEED: Acetolactate synthase large subunit (EC 2.2.1.6)
KEGG: acetolactate synthase I/II/III large subunit

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 PP_1113 Pyridoxal-phosphate dependent enzyme family protein -0.38
2 PP_5053 Protein-export protein SecB -0.35
3 PP_2387 conserved protein of unknown function -0.33
4 PP_1909 putative septum formation protein -0.32
5 PP_4204 antitoxin of the type II toxin-antitoxin MqsRA system and DNA-binding transcriptional repressor -0.31
6 PP_0850 Dual-specificity RNA methyltransferase RlmN -0.31
7 PP_2379 putative cytochrome oxidase biogenesis protein -0.31
8 PP_0872 Peptide chain release factor 3 -0.30
9 PP_1007 putative Transmembrane sensor -0.30
10 PP_2363 conserved protein of unknown function -0.29
11 PP_1623 RNA polymerase, sigma S (sigma 38) factor -0.29
12 PP_2148 transcription-repair coupling factor -0.29
13 PP_3620 cofactor of beta-methylthiolation of ribosomal protein S12 -0.29
14 PP_5101 coproporphyrinogen/heterocyclic compound oxidase (aerobic) -0.27
15 PP_1232 conserved exported protein of unknown function -0.27
16 PP_4171 conserved exported protein of unknown function -0.27
17 PP_1000 ornithine carbamoyltransferase, catabolic -0.27
18 PP_2458 ribokinase -0.26
19 PP_4620 Fumarylacetoacetase -0.26
20 PP_1807 2-dehydro-3-deoxyphosphooctonate aldolase -0.26

Or look for positive cofitness