Negative cofitness for PP_4666 from Pseudomonas putida KT2440

3-hydroxyisobutyrate dehydrogenase
SEED: 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31)
KEGG: 3-hydroxyisobutyrate dehydrogenase

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	PP_5288		Phosphomannomutase/phosphoglucomutase	-0.14
2	PP_1074		DNA-binding transcriptional repressor - GlpR-glycerol-3-phosphate	-0.14
3	PP_0940		putative protease involved in Microcin B17 maturation and in sensitivity to the DNA gyrase inhibitor LetD	-0.14
4	PP_2457		DNA-binding transcriptional repressor	-0.13
5	PP_0676		putative Transcription elongation factor	-0.13
6	PP_2458		ribokinase	-0.13
7	PP_2323		conserved protein of unknown function	-0.12
8	PP_1827		N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase	-0.12
9	PP_0850		Dual-specificity RNA methyltransferase RlmN	-0.12
10	PP_0942		regulatory protease	-0.11
11	PP_3578		phosphoglucomutase	-0.11
12	PP_5284		UPF0758 protein PP_5284	-0.11
13	PP_0137		glutamate/aspartate-proton DAACS transporter	-0.11
14	PP_4980		ATP-dependent RNA helicase	-0.11
15	PP_0540		conserved inner membrane protein	-0.11
16	PP_4050		glycogen synthase	-0.11
17	PP_2590		Outer membrane ferric siderophore receptor	-0.11
18	PP_1452		MutT/nudix family protein	-0.11
19	PP_1777		phosphomannomutase	-0.11
20	PP_0333		conserved exported protein of unknown function	-0.10

Or look for positive cofitness