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  • Negative cofitness for PP_4583 from Pseudomonas putida KT2440

    putative Peptidase
    SEED: Protease II (EC 3.4.21.83)
    KEGG: oligopeptidase B

    Computing cofitness values with 989 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 PP_0362 Biotin synthase -0.24
    2 PP_1681 cobalamin 5'-phosphate synthase / Cobalamin synthase -0.23
    3 PP_0291 conserved protein of unknown function -0.23
    4 PP_5370 Oxidoreductase-related protein -0.23
    5 PP_5303 aminoacrylate/iminopropionate hydrolase/deaminase -0.23
    6 PP_1672 cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase -0.23
    7 PP_0289 Imidazoleglycerol-phosphate dehydratase -0.22
    8 PP_3186 putative Transcriptional activator -0.21
    9 PP_4830 precorrin-6Y C(5,15)-methyltransferase -0.21
    10 PP_4977 5,10-methylenetetrahydrofolate reductase -0.21
    11 PP_0293 Imidazole glycerol phosphate synthase subunit HisF -0.21
    12 PP_4827 Precorrin-2 C(20)-methyltransferase -0.21
    13 PP_2375 cobalamin-dependent methionine synthase -0.20
    14 PP_1677 Adenosyl-cobyric acid synthase -0.20
    15 PP_5098 methionine biosynthesis protein MetW -0.20
    16 PP_1673 cobyrinate a,c-diamide synthase -0.20
    17 PP_3507 Aerobic cobaltochelatase subunit CobN -0.20
    18 PP_0967 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) -0.20
    19 PP_1679 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase -0.20
    20 PP_5097 homoserine O-acetyltransferase -0.20

    Or look for positive cofitness