Negative cofitness for PP_4549 from Pseudomonas putida KT2440

long-chain-fatty-acid/CoA ligase
SEED: Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
KEGG: long-chain acyl-CoA synthetase

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	PP_5003		poly(3-hydroxyalkanoate) polymerase 1	-0.52
2	PP_5005		Poly(3-hydroxyalkanoate) polymerase 2	-0.46
3	PP_5006		Transcriptional regulator, TetR family	-0.45
4	PP_1113		Pyridoxal-phosphate dependent enzyme family protein	-0.37
5	PP_5053		Protein-export protein SecB	-0.29
6	PP_3651		Sensor histidine kinase/response regulator	-0.28
7	PP_4171		conserved exported protein of unknown function	-0.23
8	PP_1761		diguanylate cyclase with phosphodiesterase domain	-0.23
9	PP_1875		Sensor histidine kinase/response regulator	-0.22
10	PP_4217		outer membrane ferripyoverdine receptor FpvA, TonB-dependent	-0.22
11	PP_4100		Transcriptional regulator, Cro/CI family	-0.22
12	PP_4683		transglycosylase/transpeptidase	-0.21
13	PP_1698		Major facilitator family transporter	-0.21
14	PP_5146		RNA pyrophosphohydrolase	-0.21
15	PP_4785		conserved exported protein of unknown function	-0.20
16	PP_3546		Sensory box histidine kinase/response regulator	-0.20
17	PP_4281		guanine deaminase	-0.20
18	PP_2323		conserved protein of unknown function	-0.20
19	PP_5145		phosphoenolpyruvate-dependent regulator (with NPR and NTR proteins)	-0.19
20	PP_2098		D-alanyl-D-alanine carboxypeptidase	-0.19

Or look for positive cofitness