Negative cofitness for PP_4541 from Pseudomonas putida KT2440

peptidyl-prolyl cis-trans isomerase A (rotamase A)
SEED: Peptidyl-prolyl cis-trans isomerase PpiA precursor (EC 5.2.1.8)
KEGG: peptidyl-prolyl cis-trans isomerase A (cyclophilin A)

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	PP_1000		ornithine carbamoyltransferase, catabolic	-0.19
2	PP_3073		3-hydroxybutyrate dehydrogenase	-0.18
3	PP_3427		Multidrug efflux RND outer membrane protein OprN	-0.17
4	PP_4538		FMN-dependent NADH-azoreductase 2	-0.17
5	PP_4589		D-isomer specific 2-hydroxyacid dehydrogenase family protein	-0.16
6	PP_4879		23S rRNA (guanosine-2'-O-)-methyltransferase RlmB	-0.16
7	PP_4880		exoribonuclease R	-0.15
8	PP_3907		conserved protein of unknown function	-0.15
9	PP_1197		ribosomal protein S12 methylthiotransferase	-0.15
10	PP_0123		DNA polymerase I, 5	-0.15
11	PP_2319		conserved protein of unknown function	-0.15
12	PP_5486		conserved protein of unknown function	-0.15
13	PP_2694		Aldehyde dehydrogenase family protein	-0.15
14	PP_5514		conserved protein of unknown function	-0.15
15	PP_0711		putative hydrolase	-0.14
16	PP_2616		conserved protein of unknown function	-0.14
17	PP_4988		signal transduction histidine kinase CheA/CheY-like receiver	-0.14
18	PP_0247		Osmolarity sensor protein EnvZ	-0.14
19	PP_3018		conserved protein of unknown function	-0.14
20	PP_5171		sulfate ABC transporter	-0.14

Or look for positive cofitness