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  • Negative cofitness for PP_4404 from Pseudomonas putida KT2440

    dihydrolipoyl dehydrogenase component of branched-chain alpha-keto acid dehydrogenase complex
    SEED: Dihydrolipoamide dehydrogenase of branched-chain alpha-keto acid dehydrogenase (EC 1.8.1.4)
    KEGG: dihydrolipoamide dehydrogenase

    Computing cofitness values with 989 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 PP_4756 gamma-aminobutyrate permease -0.29
    2 PP_4776 AsnC family transcriptional regulator -0.28
    3 PP_1059 Uncharacterized amino acid permease YtnA -0.27
    4 PP_3415 Transcriptional regulator, LacI family -0.26
    5 PP_2389 conserved protein of unknown function -0.24
    6 PP_0987 L-serine dehydratase -0.22
    7 PP_2390 Transcriptional regulator, LysR family -0.19
    8 PP_4840 D-alanine, beta-alanine, D-serine, glycine permease -0.19
    9 PP_2388 Transporter, LysE family -0.19
    10 PP_2457 DNA-binding transcriptional repressor -0.19
    11 PP_3957 choline/carnitine/betaine transporter BetTC -0.18
    12 PP_2144 Transcriptional regulator, TetR family -0.17
    13 PP_2248 putative transporter -0.16
    14 PP_0298 AraC-family transcriptional regulator -0.15
    15 PP_1978 Transcriptional regulator, TetR family -0.15
    16 PP_0984 conserved membrane protein of unknown function -0.15
    17 PP_4059 fused trehalose synthase B/maltokinase -0.15
    18 PP_4697 poly(A) polymerase -0.15
    19 PP_2458 ribokinase -0.14
    20 PP_1236 putative Glycine cleavage system transcriptional repressor -0.14

    Or look for positive cofitness