Negative cofitness for PP_4402 from Pseudomonas putida KT2440

branched-chain alpha-keto acid dehydrogenase complex, beta subunit
SEED: Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4)
KEGG: 2-oxoisovalerate dehydrogenase E1 component, beta subunit

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 PP_4776 AsnC family transcriptional regulator -0.38
2 PP_3286 DNA-binding transcriptional repressor PaaX(phenylacetyl-CoA) -0.30
3 PP_2389 conserved protein of unknown function -0.29
4 PP_4697 poly(A) polymerase -0.23
5 PP_3415 Transcriptional regulator, LacI family -0.22
6 PP_4011 isocitrate dehydrogenase, NADP(+)-specific -0.21
7 PP_1059 Uncharacterized amino acid permease YtnA -0.21
8 PP_2082 phosphoenolpyruvate synthetase -0.20
9 PP_4756 gamma-aminobutyrate permease -0.20
10 PP_2430 Transcriptional regulator, AraC family -0.19
11 PP_2390 Transcriptional regulator, LysR family -0.19
12 PP_0339 Pyruvate dehydrogenase E1 component -0.18
13 PP_2387 conserved protein of unknown function -0.18
14 PP_4006 Putative arginyl-tRNA--protein transferase -0.18
15 PP_1074 DNA-binding transcriptional repressor - GlpR-glycerol-3-phosphate -0.18
16 PP_2457 DNA-binding transcriptional repressor -0.17
17 PP_2458 ribokinase -0.17
18 PP_4484 histidine / lysine / arginine / ornithine ABC transporter - permease subunit -0.17
19 PP_2388 Transporter, LysE family -0.17
20 PP_0987 L-serine dehydratase -0.16

Or look for positive cofitness