Negative cofitness for PP_4401 from Pseudomonas putida KT2440

branched-chain alpha-keto acid dehydrogenase complex, alpha subunit
SEED: Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4)
KEGG: 2-oxoisovalerate dehydrogenase E1 component, alpha subunit

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	PP_4776		AsnC family transcriptional regulator	-0.34
2	PP_2389		conserved protein of unknown function	-0.27
3	PP_3286		DNA-binding transcriptional repressor PaaX(phenylacetyl-CoA)	-0.27
4	PP_4011		isocitrate dehydrogenase, NADP(+)-specific	-0.22
5	PP_4697		poly(A) polymerase	-0.22
6	PP_4484		histidine / lysine / arginine / ornithine ABC transporter - permease subunit	-0.22
7	PP_4756		gamma-aminobutyrate permease	-0.21
8	PP_3415		Transcriptional regulator, LacI family	-0.21
9	PP_1059		Uncharacterized amino acid permease YtnA	-0.21
10	PP_2457		DNA-binding transcriptional repressor	-0.20
11	PP_4483		histidine lysine / arginine / ornithine ABC transporter - ATP binding subunit	-0.19
12	PP_2387		conserved protein of unknown function	-0.19
13	PP_2430		Transcriptional regulator, AraC family	-0.19
14	PP_2458		ribokinase	-0.19
15	PP_1074		DNA-binding transcriptional repressor - GlpR-glycerol-3-phosphate	-0.19
16	PP_2082		phosphoenolpyruvate synthetase	-0.18
17	PP_0339		Pyruvate dehydrogenase E1 component	-0.18
18	PP_4486		lysine / arginine / ornithine ABC transporter - periplasmic binding protein	-0.17
19	PP_4006		Putative arginyl-tRNA--protein transferase	-0.17
20	PP_4485		histidine / lysine / arginine / ornithine ABC transporter - permease subunit	-0.17

Or look for positive cofitness