Negative cofitness for PP_4116 from Pseudomonas putida KT2440

isocitrate lyase
SEED: Isocitrate lyase (EC 4.1.3.1)
KEGG: isocitrate lyase

Computing cofitness values with 1005 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	PP_5003		poly(3-hydroxyalkanoate) polymerase 1	-0.36
2	PP_5005		Poly(3-hydroxyalkanoate) polymerase 2	-0.32
3	PP_5006		Transcriptional regulator, TetR family	-0.29
4	PP_1761		diguanylate cyclase with phosphodiesterase domain	-0.28
5	PP_1113		Pyridoxal-phosphate dependent enzyme family protein	-0.26
6	PP_3651		Sensor histidine kinase/response regulator	-0.25
7	PP_5053		Protein-export protein SecB	-0.24
8	PP_4785		conserved exported protein of unknown function	-0.22
9	PP_1444		quinoprotein glucose dehydrogenase	-0.22
10	PP_2325		2-dehydropantoate 2-reductase	-0.22
11	PP_2437		putative Acyl-CoA dehydrogenase	-0.22
12	PP_4059		fused trehalose synthase B/maltokinase	-0.21
13	PP_2712		conserved exported protein of unknown function	-0.21
14	PP_5350		Transcriptional regulator, RpiR family	-0.21
15	PP_1362		pyruvate kinase II	-0.21
16	PP_0339		Pyruvate dehydrogenase E1 component	-0.20
17	PP_4980		ATP-dependent RNA helicase	-0.19
18	PP_5076		L-glutamate synthase(NADPH) alpha subunit	-0.19
19	PP_3546		Sensory box histidine kinase/response regulator	-0.19
20	PP_2144		Transcriptional regulator, TetR family	-0.19

Or look for positive cofitness