Negative cofitness for PP_4066 from Pseudomonas putida KT2440

methylglutaconyl-CoA hydratase
SEED: Methylglutaconyl-CoA hydratase (EC 4.2.1.18)
KEGG: methylglutaconyl-CoA hydratase

Computing cofitness values with 1005 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	PP_1025		2-isopropylmalate synthase	-0.23
2	PP_1655		23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	-0.23
3	PP_3286		DNA-binding transcriptional repressor PaaX(phenylacetyl-CoA)	-0.22
4	PP_2430		Transcriptional regulator, AraC family	-0.22
5	PP_1304		sulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase	-0.21
6	PP_4246		Periplasmic binding protein	-0.21
7	PP_2168		Transaldolase	-0.21
8	PP_1303		Sulfate adenylyltransferase subunit 2	-0.20
9	PP_2328		Phosphoadenosine phosphosulfate reductase	-0.20
10	PP_1656		ATP:GTP 3'-pyrophosphotransferase	-0.19
11	PP_4694		Glutamyl-Q tRNA(Asp) synthetase	-0.19
12	PP_2231		putative permease of the drug/metabolite transporter (DMT) superfamily	-0.19
13	PP_1988		3-isopropylmalate dehydrogenase	-0.19
14	PP_1986		3-isopropylmalate dehydratase small subunit	-0.18
15	PP_4006		Putative arginyl-tRNA--protein transferase	-0.17
16	PP_0420		aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex	-0.17
17	PP_1794		conserved hypothetical protein	-0.17
18	PP_0675		glutamate dehydrogenase, NADP-dependent	-0.17
19	PP_5740		protein of unknown function	-0.17
20	PP_1985		3-isopropylmalate dehydratase large subunit	-0.17

Or look for positive cofitness