Negative cofitness for PP_4064 from Pseudomonas putida KT2440

isovaleryl-CoA dehydrogenase
SEED: Isovaleryl-CoA dehydrogenase (EC 1.3.8.4)
KEGG: isovaleryl-CoA dehydrogenase

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 PP_2430 Transcriptional regulator, AraC family -0.25
2 PP_5195 putative Iron ABC transporter, permease protein -0.24
3 PP_5314 Rubredoxin-NAD(+) reductase -0.23
4 PP_3286 DNA-binding transcriptional repressor PaaX(phenylacetyl-CoA) -0.22
5 PP_4881 putative Iron ABC transporter, periplasmic iron-binding protein -0.19
6 PP_1078 putative ABC transporter, ATP-binding protein -0.19
7 PP_4006 Putative arginyl-tRNA--protein transferase -0.18
8 PP_2082 phosphoenolpyruvate synthetase -0.18
9 PP_4882 Iron ABC transporter, permease protein -0.17
10 PP_5331 Long-chain acyl-CoA thioester hydrolase -0.16
11 PP_2680 aldehyde dehydrogenase -0.16
12 PP_4776 AsnC family transcriptional regulator -0.16
13 PP_0889 conserved exported protein of unknown function -0.16
14 PP_0510 Thioredoxin -0.16
15 PP_4228 conserved protein of unknown function -0.15
16 PP_2101 DNA-binding response regulator in two-component regulatory system with EvgS -0.15
17 PP_2245 Transcriptional regulator, Cro/CI family -0.15
18 PP_0539 glucose-regulated peptidase -0.15
19 PP_1304 sulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase -0.14
20 PP_0523 conserved membrane protein of unknown function -0.14

Or look for positive cofitness