Negative cofitness for PP_3778 from Pseudomonas putida KT2440

Pyrroline-5-carboxylate reductase
SEED: Pyrroline-5-carboxylate reductase (EC 1.5.1.2)

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	PP_2388		Transporter, LysE family	-0.24
2	PP_2390		Transcriptional regulator, LysR family	-0.24
3	PP_3786		aminotransferase	-0.23
4	PP_3790		diaminopimelate epimerase	-0.21
5	PP_4684		conserved protein of unknown function with kinase-like domain	-0.20
6	PP_3376		putative phosphonate dehydrogenase	-0.19
7	PP_0120		putative zinc ABC transporter	-0.18
8	PP_1063		DNA-binding transcriptional regulator, homocysteine-binding	-0.18
9	PP_0114		methionine ABC transporter ATP-binding protein	-0.17
10	PP_1009		glyceraldehyde-3-phosphate dehydrogenase	-0.17
11	PP_2389		conserved protein of unknown function	-0.17
12	PP_3813		3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II	-0.17
13	PP_3788		putative Non-ribosomal peptide synthetase	-0.17
14	PP_5160		conserved exported protein of unknown function	-0.16
15	PP_0989		glycine cleavage system H protein 1	-0.16
16	PP_3443		putative glyceraldehyde-3-phosphate dehydrogenase	-0.16
17	PP_5238		conserved protein of unknown function	-0.16
18	PP_1348		putative MutT/nudix family protein/thiamine-phosphate pyrophosphorylase	-0.15
19	PP_1426		L-aspartate oxidase	-0.15
20	PP_0117		Zn(2+) ABC transporter - permease subunit	-0.15

Or look for positive cofitness