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  • Negative cofitness for PP_3754 from Pseudomonas putida KT2440

    Beta-ketothiolase BktB
    SEED: 3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9)
    KEGG: acetyl-CoA C-acetyltransferase

    Computing cofitness values with 989 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 PP_3651 Sensor histidine kinase/response regulator -0.28
    2 PP_0353 Exonuclease -0.22
    3 PP_5200 proline aminopeptidase P II -0.21
    4 PP_0179 putative efflux transporter -0.20
    5 PP_0858 putative methionine/glutamine aminotransferase -0.20
    6 PP_3656 putative Aromatic compound-specific porin -0.19
    7 PP_1761 diguanylate cyclase with phosphodiesterase domain -0.19
    8 PP_2144 Transcriptional regulator, TetR family -0.18
    9 PP_2389 conserved protein of unknown function -0.17
    10 PP_4050 glycogen synthase -0.17
    11 PP_4100 Transcriptional regulator, Cro/CI family -0.16
    12 PP_0176 putative efflux transporter -0.16
    13 PP_5053 Protein-export protein SecB -0.16
    14 PP_3801 putative Cation ABC transporter, periplasmic cation-binding protein -0.16
    15 PP_3842 conserved protein of unknown function -0.16
    16 PP_2390 Transcriptional regulator, LysR family -0.15
    17 PP_2325 2-dehydropantoate 2-reductase -0.15
    18 PP_0859 putative ketoglutaramate omega-amidase -0.15
    19 PP_0137 glutamate/aspartate-proton DAACS transporter -0.15
    20 PP_3532 Transcriptional regulator, AsnC family -0.15

    Or look for positive cofitness