Negative cofitness for PP_3433 from Pseudomonas putida KT2440

4-hydroxyphenylpyruvate dioxygenase
SEED: 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27)
KEGG: 4-hydroxyphenylpyruvate dioxygenase

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	PP_3999		Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase	-0.20
2	PP_1654		cysteine synthase B	-0.18
3	PP_2000		amidophosphoribosyl transferase	-0.18
4	PP_0030		metal-sensor histidine kinase	-0.17
5	PP_2370		conserved protein of unknown function	-0.17
6	PP_2371		Sulphite reductase hemoprotein, beta subunit	-0.17
7	PP_5014		Phosphoribosyl-AMP cyclohydrolase	-0.17
8	PP_0293		Imidazole glycerol phosphate synthase subunit HisF	-0.16
9	PP_1888		Fimbrial protein	-0.16
10	PP_0691		Glutamate 5-kinase	-0.16
11	PP_4999		dihydroorotase-like protein	-0.15
12	PP_4724		Carbamoyl-phosphate synthase small chain	-0.15
13	PP_1656		ATP:GTP 3'-pyrophosphotransferase	-0.15
14	PP_0082		tryptophan synthase alpha chain	-0.15
15	PP_4680		acetohydroxybutanoate synthase / acetolactate synthase	-0.15
16	PP_4723		Carbamoyl-phosphate synthase large chain	-0.15
17	PP_0421		Anthranilate phosphoribosyltransferase	-0.15
18	PP_0966		Histidinol dehydrogenase	-0.15
19	PP_5098		methionine biosynthesis protein MetW	-0.14
20	PP_0144		Metalloprotease, insulinase family	-0.14

Or look for positive cofitness