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  • Negative cofitness for PP_3376 from Pseudomonas putida KT2440

    putative phosphonate dehydrogenase
    SEED: 2-ketogluconate 6-phosphate reductase (EC 1.1.1.43)
    KEGG: phosphogluconate 2-dehydrogenase

    Computing cofitness values with 989 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 PP_3831 conserved protein of unknown function -0.45
    2 PP_2210 LysR family transcriptional regulator -0.37
    3 PP_1629 Protein RecA -0.36
    4 PP_5310 junction-specific ATP-dependent DNA helicase -0.34
    5 PP_1783 dTDP-glucose pyrophosphorylase -0.34
    6 PP_4124 NADH-quinone oxidoreductase subunit G -0.34
    7 PP_4121 NADH-quinone oxidoreductase subunit C/D -0.33
    8 PP_4131 NADH-quinone oxidoreductase subunit N -0.33
    9 PP_2927 conserved protein of unknown function -0.33
    10 PP_2336 aconitate hydratase 1 -0.33
    11 PP_t11 tRNA-Lys -0.32
    12 PP_4129 NADH:ubiquinone oxidoreductase, membrane subunit L -0.32
    13 PP_4120 NADH-quinone oxidoreductase subunit B -0.31
    14 PP_0393 putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase -0.31
    15 PP_t29 tRNA-Ala -0.31
    16 PP_2933 GSH-dependent disulfide bond oxidoreductase -0.31
    17 PP_2889 putative Transmembrane regulator PrtR -0.30
    18 PP_1734 Probable septum site-determining protein MinC -0.30
    19 PP_4611 RNA polymerase sigma-70 factor, ECF subfamily -0.30
    20 PP_2025 Exonuclease SbcD -0.30

    Or look for positive cofitness