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  • Negative cofitness for PP_3356 from Pseudomonas putida KT2440

    p-coumarate CoA-ligase (EC 6.2.1.12) (from data)
    Original annotation: feruloyl-CoA-synthetase
    KEGG: feruloyl-CoA synthase

    Computing cofitness values with 989 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 PP_5053 Protein-export protein SecB -0.23
    2 PP_3651 Sensor histidine kinase/response regulator -0.18
    3 PP_5200 proline aminopeptidase P II -0.18
    4 PP_5110 cytokinetic ring ABC transporter-like subunit - ATP-binding subunit -0.16
    5 PP_5433 putative NADH:ubiquinone oxidoreductase subunit 2 -0.16
    6 PP_5173 RND efflux transporter -0.15
    7 PP_3546 Sensory box histidine kinase/response regulator -0.14
    8 PP_3404 conserved protein of unknown function -0.14
    9 PP_4551 Hydrolase, alpha/beta fold family -0.14
    10 PP_4398 Major facilitator family transporter -0.14
    11 PP_5588 conserved protein of unknown function -0.13
    12 PP_1775 Metallo-beta-lactamase family protein -0.13
    13 PP_2431 Transcriptional regulator, LysR family -0.13
    14 PP_4940 Putative glycosyltransferase -0.13
    15 PP_2866 FMN-dependent NADH-azoreductase 1 -0.12
    16 PP_1799 GDP-mannose 4,6-dehydratase -0.12
    17 PP_2702 putative Porin -0.12
    18 PP_2289 conserved exported protein of unknown function -0.12
    19 PP_5109 membrane component of the ABC transporter FtsEX involved in cellular division -0.12
    20 PP_1909 putative septum formation protein -0.12

    Or look for positive cofitness