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  • Negative cofitness for PP_3080 from Pseudomonas putida KT2440

    tyr-sensitive phospho-2-dehydro-3-deoxyheptonate aldolase
    SEED: 2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase I alpha (EC 2.5.1.54)
    KEGG: 3-deoxy-7-phosphoheptulonate synthase

    Computing cofitness values with 989 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 PP_4723 Carbamoyl-phosphate synthase large chain -0.25
    2 PP_4724 Carbamoyl-phosphate synthase small chain -0.25
    3 PP_4999 dihydroorotase-like protein -0.23
    4 PP_0691 Glutamate 5-kinase -0.21
    5 PP_1264 putative Fusaric acid resistance protein -0.21
    6 PP_1266 putative Fusaric acid resistance protein -0.21
    7 PP_0833 queuine tRNA-ribosyltransferase -0.20
    8 PP_4896 DNA mismatch repair protein MutL -0.20
    9 PP_t57 tRNA-Arg -0.20
    10 PP_4100 Transcriptional regulator, Cro/CI family -0.19
    11 PP_1626 DNA mismatch repair protein MutS -0.18
    12 PP_5399 conserved protein of unknown function -0.18
    13 PP_4604 putative permease of the drug/metabolite transporter (DMT) superfamily -0.17
    14 PP_5624 conserved protein of unknown function -0.15
    15 PP_5541 conserved protein of unknown function -0.15
    16 PP_4700 pantothenate synthetase -0.15
    17 PP_4909 phosphoserine phosphatase -0.15
    18 PP_4465 putative Porin -0.14
    19 PP_2000 amidophosphoribosyl transferase -0.14
    20 PP_4742 Type I restriction-modification system, S subunit -0.14

    Or look for positive cofitness