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  • Negative cofitness for PP_2549 from Pseudomonas putida KT2440

    conserved protein of unknown function
    SEED: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49)

    Computing cofitness values with 1005 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 PP_1063 DNA-binding transcriptional regulator, homocysteine-binding -0.32
    2 PP_3790 diaminopimelate epimerase -0.30
    3 PP_0506 putative ABC efflux transporter, permease protein -0.29
    4 PP_4421 putative aminotransferase -0.28
    5 PP_3786 aminotransferase -0.25
    6 PP_2714 Sensor histidine kinase -0.25
    7 PP_3376 putative phosphonate dehydrogenase -0.23
    8 PP_1348 putative MutT/nudix family protein/thiamine-phosphate pyrophosphorylase -0.23
    9 PP_5384 copper sensor protein -0.22
    10 PP_4446 putative Group II intron-encoding maturase -0.22
    11 PP_3788 putative Non-ribosomal peptide synthetase -0.21
    12 PP_4922 Phosphomethylpyrimidine synthase -0.21
    13 PP_0792 catabolite repressor-activator, DNA-binding transcriptional dual regulator -0.21
    14 PP_0662 putative Threonine synthase -0.21
    15 PP_5159 conserved protein of unknown function -0.21
    16 PP_4897 N-acetylmuramoyl-L-alanine amidase -0.21
    17 PP_1109 Transcriptional regulator, GntR family -0.20
    18 PP_4463 Carbon-nitrogen hydrolase family protein -0.20
    19 PP_4445 transposase -0.20
    20 PP_0114 methionine ABC transporter ATP-binding protein -0.20

    Or look for positive cofitness