Negative cofitness for PP_2444 from Pseudomonas putida KT2440

Transcriptional regulator, LysR family
SEED: Transcriptional regulator, LysR family
KEGG: LysR family transcriptional regulator, transcriptional activator of nhaA

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 PP_0420 aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex -0.22
2 PP_1088 Argininosuccinate synthase -0.20
3 PP_1988 3-isopropylmalate dehydrogenase -0.19
4 PP_5289 Acetylglutamate kinase -0.19
5 PP_1995 N-(5'-phosphoribosyl)anthranilate isomerase -0.19
6 PP_4909 phosphoserine phosphatase -0.19
7 PP_4678 Ketol-acid reductoisomerase -0.19
8 PP_0965 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) -0.19
9 PP_4680 acetohydroxybutanoate synthase / acetolactate synthase -0.18
10 PP_0417 Anthranilate synthase component 1 -0.18
11 PP_0421 Anthranilate phosphoribosyltransferase -0.18
12 PP_5015 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) -0.18
13 PP_5128 Dihydroxy-acid dehydratase -0.18
14 PP_0290 Imidazole glycerol phosphate synthase subunit HisH -0.18
15 PP_1985 3-isopropylmalate dehydratase large subunit -0.18
16 PP_0966 Histidinol dehydrogenase -0.18
17 PP_4890 ATP phosphoribosyltransferase regulatory subunit -0.18
18 PP_3511 Branched-chain-amino-acid aminotransferase -0.18
19 PP_0967 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) -0.17
20 PP_0289 Imidazoleglycerol-phosphate dehydratase -0.17

Or look for positive cofitness