Negative cofitness for PP_2432 from Pseudomonas putida KT2440

6,7-dihydropteridine reductase
SEED: Oxygen-insensitive NAD(P)H nitroreductase (EC 1.-.-.-) / Dihydropteridine reductase (EC 1.5.1.34)
KEGG: nitroreductase / dihydropteridine reductase

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	PP_4922		Phosphomethylpyrimidine synthase	-0.22
2	PP_1348		putative MutT/nudix family protein/thiamine-phosphate pyrophosphorylase	-0.22
3	PP_3790		diaminopimelate epimerase	-0.21
4	PP_5104		thiazole synthase	-0.20
5	PP_4723		Carbamoyl-phosphate synthase large chain	-0.20
6	PP_1110		serine acetyltransferase	-0.19
7	PP_0047		response regulator	-0.19
8	PP_1109		Transcriptional regulator, GntR family	-0.19
9	PP_3376		putative phosphonate dehydrogenase	-0.18
10	PP_1111		putative Synthetase	-0.18
11	PP_4782		Phosphomethylpyrimidine kinase	-0.18
12	PP_0237		aliphatic sulfonate ABC transporter - periplasmic binding protein / transport of isethionate	-0.18
13	PP_1063		DNA-binding transcriptional regulator, homocysteine-binding	-0.18
14	PP_1057		Transcriptional regulator, PadR family	-0.17
15	PP_2714		Sensor histidine kinase	-0.17
16	PP_3789		putative Efflux transporter	-0.17
17	PP_3788		putative Non-ribosomal peptide synthetase	-0.17
18	PP_1233		sulfurtransferase	-0.17
19	PP_0693		conserved protein of unknown function	-0.17
20	PP_4724		Carbamoyl-phosphate synthase small chain	-0.16

Or look for positive cofitness