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  • Negative cofitness for PP_2335 from Pseudomonas putida KT2440

    methylcitrate synthase
    SEED: 2-methylcitrate synthase (EC 2.3.3.5)
    KEGG: 2-methylcitrate synthase

    Computing cofitness values with 989 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 PP_1761 diguanylate cyclase with phosphodiesterase domain -0.25
    2 PP_4050 glycogen synthase -0.24
    3 PP_1875 Sensor histidine kinase/response regulator -0.23
    4 PP_2458 ribokinase -0.22
    5 PP_3651 Sensor histidine kinase/response regulator -0.22
    6 PP_2144 Transcriptional regulator, TetR family -0.22
    7 PP_0133 Alginate biosynthesis transcriptional regulatory protein AlgB -0.22
    8 PP_2663 conserved protein of unknown function -0.20
    9 PP_3578 phosphoglucomutase -0.19
    10 PP_2389 conserved protein of unknown function -0.19
    11 PP_4052 4-alpha-glucanotransferase -0.19
    12 PP_1236 putative Glycine cleavage system transcriptional repressor -0.18
    13 PP_3200 conserved exported protein of unknown function -0.18
    14 PP_2662 conserved exported protein of unknown function -0.17
    15 PP_2457 DNA-binding transcriptional repressor -0.17
    16 PP_2387 conserved protein of unknown function -0.17
    17 PP_2325 2-dehydropantoate 2-reductase -0.17
    18 PP_2664 putative hybrid sensor and regulator, histidine kinase -0.17
    19 PP_1238 putative Lipoprotein -0.16
    20 PP_3546 Sensory box histidine kinase/response regulator -0.15

    Or look for positive cofitness