Negative cofitness for PP_2136 from Pseudomonas putida KT2440

enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase
SEED: Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3)
KEGG: 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase / enoyl-CoA isomerase

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	PP_1113		Pyridoxal-phosphate dependent enzyme family protein	-0.37
2	PP_3651		Sensor histidine kinase/response regulator	-0.36
3	PP_5003		poly(3-hydroxyalkanoate) polymerase 1	-0.34
4	PP_5006		Transcriptional regulator, TetR family	-0.32
5	PP_5053		Protein-export protein SecB	-0.30
6	PP_5005		Poly(3-hydroxyalkanoate) polymerase 2	-0.29
7	PP_1875		Sensor histidine kinase/response regulator	-0.27
8	PP_0134		conserved exported protein of unknown function	-0.26
9	PP_1279		Probable alginate O-acetylase AlgJ	-0.26
10	PP_1777		phosphomannomutase	-0.25
11	PP_2741		conserved membrane protein of unknown function	-0.25
12	PP_4217		outer membrane ferripyoverdine receptor FpvA, TonB-dependent	-0.25
13	PP_3769		conserved exported protein of unknown function	-0.24
14	PP_5283		periplasmic dipeptide transport protein	-0.24
15	PP_1761		diguanylate cyclase with phosphodiesterase domain	-0.23
16	PP_0066		Ribosomal RNA small subunit methyltransferase B	-0.23
17	PP_0137		glutamate/aspartate-proton DAACS transporter	-0.23
18	PP_1871		Protease HtpX	-0.23
19	PP_1803		UDP-sugar epimerase	-0.22
20	PP_5101		coproporphyrinogen/heterocyclic compound oxidase (aerobic)	-0.22

Or look for positive cofitness