Negative cofitness for PP_2101 from Pseudomonas putida KT2440

DNA-binding response regulator in two-component regulatory system with EvgS
SEED: DNA-binding response regulator, LuxR family
KEGG: two-component system, NarL family, response regulator EvgA

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	PP_4863		high-affinity branched-chain amino acid transporter, ATP-binding	-0.25
2	PP_4866		High-affinity branched-chain amino acid transport system permease protein BraD	-0.25
3	PP_0625		Chaperone protein ClpB	-0.25
4	PP_4864		High-affinity branched-chain amino acid transport ATP-binding protein BraF	-0.24
5	PP_2080		NAD-specific glutamate dehydrogenase	-0.22
6	PP_1140		branched chain amino acid transporter - permease subunit	-0.22
7	PP_0774		Phosphate acetyltransferase	-0.21
8	PP_1141		branched-chain amino acids ABC transporter - periplasmic leucine binding subunit	-0.21
9	PP_1137		high-affinity branched-chain amino acid transporter, ATP binding	-0.20
10	PP_0881		dipeptide ABC transporter - putative membrane subunit	-0.20
11	PP_4865		High-affinity branched-chain amino acid transport system permease protein BraE	-0.19
12	PP_0878		dipeptide ABC transporter, binding subunit	-0.19
13	PP_1138		branched chain amino acid transporter - ATP binding subunit	-0.18
14	PP_3376		putative phosphonate dehydrogenase	-0.18
15	PP_3790		diaminopimelate epimerase	-0.18
16	PP_2714		Sensor histidine kinase	-0.17
17	PP_4060		Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase	-0.17
18	PP_3788		putative Non-ribosomal peptide synthetase	-0.17
19	PP_1348		putative MutT/nudix family protein/thiamine-phosphate pyrophosphorylase	-0.17
20	PP_4684		conserved protein of unknown function with kinase-like domain	-0.17

Or look for positive cofitness