Negative cofitness for PP_2047 from Pseudomonas putida KT2440

3-hydroxyacyl-CoA dehydrogenase family protein
SEED: Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3)

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	PP_4565		Isocitrate dehydrogenase kinase/phosphatase	-0.48
2	PP_4923		Outer membrane efflux protein	-0.38
3	PP_0763		Medium-chain-fatty-acid CoA ligase	-0.33
4	PP_0428		aminoacyl-adenylate hydrolase/purine nucleoside phosphoramidase	-0.24
5	PP_0248		Probable alpha-L-glutamate ligase	-0.23
6	PP_0767		Transcriptional regulator, LuxR family	-0.22
7	PP_3755		3-hydroxybutyryl-CoA dehydrogenase	-0.18
8	PP_3821		UTP-glucose-1-phosphate uridylyltransferase	-0.17
9	PP_2665		Glycerol metabolism activator	-0.17
10	PP_4940		Putative glycosyltransferase	-0.17
11	PP_5717		conserved protein of unknown function	-0.17
12	PP_4055		Glycogen debranching enzyme	-0.16
13	PP_0378		Pyrroloquinoline-quinone synthase	-0.15
14	PP_1920		conserved protein of unknown function	-0.15
15	PP_4116		isocitrate lyase	-0.14
16	PP_0376		Coenzyme PQQ synthesis protein E	-0.14
17	PP_4500		TrpH family protein	-0.14
18	PP_2667		ABC transporter	-0.14
19	PP_3104		conserved protein of unknown function	-0.14
20	PP_2675		Cytochrome c-type protein	-0.14

Or look for positive cofitness