Negative cofitness for PP_1385 from Pseudomonas putida KT2440

Probable efflux pump membrane transporter TtgB
SEED: RND efflux system, inner membrane transporter CmeB
KEGG: hydrophobic/amphiphilic exporter-1 (mainly G- bacteria), HAE1 family

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	PP_4515		Transcriptional regulator, MarR family	-0.37
2	PP_3456		Multidrug resistance protein MexB	-0.35
3	PP_2664		putative hybrid sensor and regulator, histidine kinase	-0.34
4	PP_2662		conserved exported protein of unknown function	-0.33
5	PP_1387		Probable HTH-type transcriptional regulator TtgR	-0.28
6	PP_3455		Multidrug efflux RND membrane fusion protein	-0.27
7	PP_2663		conserved protein of unknown function	-0.27
8	PP_4235		thiol/disulfide interchange protein 2	-0.24
9	PP_1875		Sensor histidine kinase/response regulator	-0.23
10	PP_2666		conserved exported protein of unknown function	-0.22
11	PP_2017		aminopeptidase N	-0.20
12	PP_1792		Glycosyl transferase, group 2 family protein	-0.20
13	PP_4236		putative Thiol:disulfide interchange protein dsbE	-0.19
14	PP_5590		conserved exported protein of unknown function	-0.19
15	PP_4529		conserved protein of unknown function	-0.18
16	PP_4762		Acyl-CoA thioesterase II	-0.18
17	PP_2450		conserved protein of unknown function	-0.18
18	PP_1793		Glycosyl transferase, group 2 family protein	-0.18
19	PP_4551		Hydrolase, alpha/beta fold family	-0.18
20	PP_1816		Alcohol dehydrogenase, zinc-containing	-0.17

Or look for positive cofitness