Negative cofitness for PP_1186 from Pseudomonas putida KT2440

two component system DNA-binding transcriptional dual regulator
SEED: Transcriptional regulatory protein PhoP
KEGG: two-component system, OmpR family, response regulator PhoP

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	PP_0291		conserved protein of unknown function	-0.27
2	PP_2168		Transaldolase	-0.27
3	PP_4977		5,10-methylenetetrahydrofolate reductase	-0.25
4	PP_1369		conserved protein of unknown function	-0.25
5	PP_1304		sulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase	-0.25
6	PP_1025		2-isopropylmalate synthase	-0.24
7	PP_0292		1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data)	-0.24
8	PP_2001		O-succinylhomoserine sulfhydrylase	-0.24
9	PP_5128		Dihydroxy-acid dehydratase	-0.24
10	PP_0967		histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data)	-0.24
11	PP_0082		tryptophan synthase alpha chain	-0.24
12	PP_5097		homoserine O-acetyltransferase	-0.23
13	PP_2375		cobalamin-dependent methionine synthase	-0.23
14	PP_1795		conserved protein of unknown function	-0.23
15	PP_4679		acetohydroxybutanoate synthase / acetolactate synthase	-0.23
16	PP_0421		Anthranilate phosphoribosyltransferase	-0.23
17	PP_5203		5-formyltetrahydrofolate cyclo-ligase	-0.23
18	PP_0966		Histidinol dehydrogenase	-0.23
19	PP_4678		Ketol-acid reductoisomerase	-0.23
20	PP_4680		acetohydroxybutanoate synthase / acetolactate synthase	-0.23

Or look for positive cofitness