Negative cofitness for PP_1141 from Pseudomonas putida KT2440

branched-chain amino acids ABC transporter - periplasmic leucine binding subunit
SEED: High-affinity leucine-specific transport system, periplasmic binding protein LivK (TC 3.A.1.4.1)
KEGG: branched-chain amino acid transport system substrate-binding protein

Computing cofitness values with 995 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	PP_4197		Transcriptional regulator, GntR family	-0.43
2	PP_4754		Transcriptional regulator, TetR family	-0.33
3	PP_2245		Transcriptional regulator, Cro/CI family	-0.30
4	PP_4947		proline dehydrogenase/1-pyrroline-5-carboxylate dehydrogenase	-0.28
5	PP_2430		Transcriptional regulator, AraC family	-0.24
6	PP_4729		factor used in recombination and DNA repair	-0.22
7	PP_0118		zinc import ATP-binding protein	-0.21
8	PP_2101		DNA-binding response regulator in two-component regulatory system with EvgS	-0.21
9	PP_4815		putative Membrane protein	-0.20
10	PP_0510		Thioredoxin	-0.20
11	PP_5313		DNA-binding protein HU-alpha	-0.20
12	PP_4342		flagellar synthesis regulator, putative ATPase	-0.18
13	PP_4817		MaoC domain protein	-0.18
14	PP_4893		GTPase HflX	-0.17
15	PP_4622		Hmg transcriptional repressor	-0.17
16	PP_1872		glutamate-pyruvate aminotransferase	-0.17
17	PP_4767		amino acid exporter for phenylalanine, threonine	-0.17
18	PP_1025		2-isopropylmalate synthase	-0.17
19	PP_1304		sulfate adenylyltransferase subunit 1/adenylyl-sulfate kinase	-0.17
20	PP_0117		Zn(2+) ABC transporter - permease subunit	-0.17

Or look for positive cofitness