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  • Negative cofitness for PP_0769 from Pseudomonas putida KT2440

    Sensor histidine kinase
    SEED: Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-)

    Computing cofitness values with 989 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 PP_1348 putative MutT/nudix family protein/thiamine-phosphate pyrophosphorylase -0.27
    2 PP_0362 Biotin synthase -0.26
    3 PP_3788 putative Non-ribosomal peptide synthetase -0.26
    4 PP_5348 Transcriptional regulator, LysR family -0.24
    5 PP_1063 DNA-binding transcriptional regulator, homocysteine-binding -0.24
    6 PP_4461 Major facilitator family transporter -0.23
    7 PP_3790 diaminopimelate epimerase -0.23
    8 PP_4246 Periplasmic binding protein -0.23
    9 PP_4434 D-amino acid dehydrogenase 1 small subunit -0.22
    10 PP_4922 Phosphomethylpyrimidine synthase -0.22
    11 PP_5303 aminoacrylate/iminopropionate hydrolase/deaminase -0.22
    12 PP_3786 aminotransferase -0.21
    13 PP_3376 putative phosphonate dehydrogenase -0.21
    14 PP_0420 aminodeoxychorismate synthase / para-aminobenzoate synthase multi-enzyme complex -0.21
    15 PP_5097 homoserine O-acetyltransferase -0.21
    16 PP_4882 Iron ABC transporter, permease protein -0.20
    17 PP_5098 methionine biosynthesis protein MetW -0.20
    18 PP_5346 pyruvate carboxylase subunit B -0.20
    19 PP_5347 pyruvate carboxylase subunit A -0.20
    20 PP_2001 O-succinylhomoserine sulfhydrylase -0.20

    Or look for positive cofitness