Negative cofitness for PP_0362 from Pseudomonas putida KT2440

Biotin synthase
SEED: Biotin synthase (EC 2.8.1.6)
KEGG: biotin synthetase

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 PP_4892 integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex -0.36
2 PP_1445 carbohydrate-selective porin -0.36
3 PP_5084 penicillin-insensitive transglycosylase/penicillin-sensitive transpeptidase -0.34
4 PP_2331 conserved membrane protein of unknown function -0.34
5 PP_4204 antitoxin of the type II toxin-antitoxin MqsRA system and DNA-binding transcriptional repressor -0.33
6 PP_4880 exoribonuclease R -0.33
7 PP_1909 putative septum formation protein -0.32
8 PP_2330 conserved protein of unknown function -0.31
9 PP_4008 ATP-dependent serine protease -0.30
10 PP_0872 Peptide chain release factor 3 -0.30
11 PP_0806 putative Surface adhesion protein -0.30
12 PP_0804 Protein secretion ABC efflux system, permease and ATP-binding protein -0.30
13 PP_4342 flagellar synthesis regulator, putative ATPase -0.30
14 PP_1113 Pyridoxal-phosphate dependent enzyme family protein -0.29
15 PP_0805 Outer membrane efflux protein -0.28
16 PP_2363 conserved protein of unknown function -0.28
17 PP_0850 Dual-specificity RNA methyltransferase RlmN -0.28
18 PP_1504 conserved protein of unknown function -0.28
19 PP_3831 conserved protein of unknown function -0.28
20 PP_2332 conserved exported protein of unknown function -0.27

Or look for positive cofitness