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  • Negative cofitness for PP_0279 from Pseudomonas putida KT2440

    conserved protein of unknown function
    SEED: SAM-dependent methyltransferases

    Computing cofitness values with 989 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 PP_1655 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD -0.26
    2 PP_1656 ATP:GTP 3'-pyrophosphotransferase -0.26
    3 PP_4984 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase -0.25
    4 PP_0364 pimeloyl-[acp] methyl ester esterase -0.25
    5 PP_0363 8-amino-7-oxononanoate synthase -0.24
    6 PP_2231 putative permease of the drug/metabolite transporter (DMT) superfamily -0.24
    7 PP_0366 dethiobiotin synthetase -0.23
    8 PP_0365 Malonyl-[acyl-carrier protein] O-methyltransferase -0.23
    9 PP_4696 Nitrogen regulation protein NR(I) -0.23
    10 PP_4830 precorrin-6Y C(5,15)-methyltransferase -0.23
    11 PP_1675 Subunit of adenosylcobinamide-phosphate synthase beta component -0.22
    12 PP_5639 conserved exported protein of unknown function -0.22
    13 PP_1650 Sensor protein GacS -0.21
    14 PP_4804 RlpA-like lipoprotein -0.21
    15 PP_3233 transcriptional regulator with 4Fe-4S cluster, Crp/Fnr family -0.21
    16 PP_4099 two-componenent system BarA/UvrY - regulatory subunit -0.21
    17 PP_4694 Glutamyl-Q tRNA(Asp) synthetase -0.20
    18 PP_4977 5,10-methylenetetrahydrofolate reductase -0.20
    19 PP_4827 Precorrin-2 C(20)-methyltransferase -0.20
    20 PP_3417 D-gluconate transporter -0.20

    Or look for positive cofitness