Negative cofitness for PP_0274 from Pseudomonas putida KT2440

putative transcriptional regulator containing HTH domain
SEED: helix-turn-helix domain protein

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	PP_4862		3-hydroxy acid dehydrogenase, NADP-dependent / malonic semialdehyde reductase	-0.21
2	PP_5566		protein of unknown function	-0.21
3	PP_2487		putative aldehyde dehydrogenase	-0.19
4	PP_3245		conserved protein of unknown function	-0.19
5	PP_2072		Transcriptional regulator, AraC family	-0.18
6	PP_5389		conserved hypothetical protein	-0.18
7	PP_4572		conserved exported protein of unknown function	-0.18
8	PP_3990		substrate or modulator of FtsH-mediated proteolysis	-0.17
9	PP_2171		Transporter, LysE family	-0.17
10	PP_3857		conserved protein of unknown function	-0.17
11	PP_0026		putative cobalt/cadmium/zinc exporter	-0.17
12	PP_2236		putative hydrolase of the alpha/beta superfamily	-0.17
13	PP_0873		putrescine-binding periplasmic protein	-0.16
14	PP_5391		conserved hypothetical protein	-0.16
15	PP_0611		Type IV pili biogenesis protein PilE	-0.16
16	PP_4446		putative Group II intron-encoding maturase	-0.16
17	PP_4155		putative amine oxidase	-0.16
18	PP_1072		Leucine-rich repeat domain protein	-0.16
19	PP_2276		putative phage exonuclease	-0.16
20	PP_3419		Sigma-54 dependent transcriptional regulator/response regulator	-0.16

Or look for positive cofitness