Negative cofitness for PP_0185 from Pseudomonas putida KT2440

Positive alginate biosynthesis regulatory protein
SEED: Autolysis response regulater LytR
KEGG: two-component system, LytT family, response regulator AlgR

Computing cofitness values with 989 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	PP_1104		AotO-related protein	-0.30
2	PP_0574		DNA-binding response regulator, LuxR family	-0.30
3	PP_1444		quinoprotein glucose dehydrogenase	-0.29
4	PP_1006		putative outer membrane heme receptor	-0.28
5	PP_1656		ATP:GTP 3'-pyrophosphotransferase	-0.28
6	PP_3691		DNA helicase-related protein	-0.26
7	PP_1655		23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	-0.26
8	PP_4924		Serine protease, subtilase family	-0.26
9	PP_2000		amidophosphoribosyl transferase	-0.25
10	PP_0742		conserved exported protein of unknown function	-0.24
11	PP_0043		cation efflux system protein	-0.23
12	PP_1236		putative Glycine cleavage system transcriptional repressor	-0.23
13	PP_0803		Protein secretion ABC efflux system, membrane fusion protein	-0.23
14	PP_3999		Uroporphyrinogen-III C-methyltransferase/Precorrin-2 dehydrogenase/Sirohydrochlorin ferrochelatase	-0.22
15	PP_4863		high-affinity branched-chain amino acid transporter, ATP-binding	-0.22
16	PP_4964		D-erythrose 4-phosphate dehydrogenase	-0.22
17	PP_0026		putative cobalt/cadmium/zinc exporter	-0.22
18	PP_4866		High-affinity branched-chain amino acid transport system permease protein BraD	-0.22
19	PP_1654		cysteine synthase B	-0.21
20	PP_1781		putative O-acyltransferase	-0.21

Or look for positive cofitness