Negative cofitness for HEPCGN_00425 from Escherichia coli ECOR38

AlpA family transcriptional regulator
SEED: COG3311: Predicted transcriptional regulator

Computing cofitness values with 58 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	HEPCGN_10785		ligand-gated channel	-0.51
2	HEPCGN_20655	glyA	serine hydroxymethyltransferase	-0.46
3	HEPCGN_24490		DUF935 domain-containing protein	-0.46
4	HEPCGN_03335		restriction endonuclease	-0.45
5	HEPCGN_18925	xdhD	putative hypoxanthine oxidase XdhD	-0.44
6	HEPCGN_10465	yjeT	Uncharacterized protein YjeT	-0.43
7	HEPCGN_12345	metB	cystathionine gamma-synthase	-0.43
8	HEPCGN_01455	tolR	colicin uptake protein TolR	-0.42
9	HEPCGN_01800	fiu	catecholate siderophore receptor Fiu	-0.42
10	HEPCGN_21325	cysP	thiosulfate/sulfate ABC transporter substrate-binding protein CysP	-0.42
11	HEPCGN_19085	cysH	phosphoadenosine phosphosulfate reductase	-0.41
12	HEPCGN_10025	argF	ornithine carbamoyltransferase	-0.41
13	HEPCGN_01470	pal	peptidoglycan-associated lipoprotein Pal	-0.41
14	HEPCGN_23030	serC	3-phosphoserine/phosphohydroxythreonine transaminase	-0.41
15	HEPCGN_07685	lysR	LysR family transcriptional regulator	-0.41
16	HEPCGN_23035	aroA	3-phosphoshikimate 1-carboxyvinyltransferase	-0.41
17	HEPCGN_13030	metR	HTH-type transcriptional regulator MetR	-0.41
18	HEPCGN_03190	hisIE	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE	-0.40
19	HEPCGN_03210	hisB	bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB	-0.40
20	HEPCGN_05580	aroD	3-dehydroquinate dehydratase	-0.40

Or look for positive cofitness