Negative cofitness for GFF937 from Variovorax sp. SCN45

Biotin synthase (EC 2.8.1.6)
SEED: Biotin synthase (EC 2.8.1.6)
KEGG: biotin synthetase

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 GFF2576 6-carboxy-5,6,7,8-tetrahydropterin synthase (EC 4.1.2.50) -0.74
2 GFF6017 NADPH-dependent 7-cyano-7-deazaguanine reductase (EC 1.7.1.13) -0.69
3 GFF1861 Transcriptional regulator, IclR family -0.68
4 GFF341 ATP-dependent Clp protease ATP-binding subunit ClpA -0.66
5 GFF5483 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits -0.65
6 GFF2455 Transcriptional regulator RutR of pyrimidine catabolism (TetR family) -0.60
7 GFF5521 Ribosomal-protein-S18p-alanine acetyltransferase (EC 2.3.1.128) -0.60
8 GFF7306 FolM Alternative dihydrofolate reductase 1 -0.57
9 GFF4529 Probable signal peptide protein -0.57
10 GFF4176 Transcriptional activator MetR -0.56
11 GFF5262 Ferric iron ABC transporter, iron-binding protein -0.55
12 GFF496 Squalene synthase (EC 2.5.1.21) -0.55
13 GFF5383 DNA topoisomerase III, Burkholderia type (EC 5.99.1.2) -0.55
14 GFF3071 ADP-ribose pyrophosphatase of COG1058 family (EC 3.6.1.13) -0.54
15 GFF232 Arginine decarboxylase (EC 4.1.1.19); Ornithine decarboxylase (EC 4.1.1.17); Lysine decarboxylase (EC 4.1.1.18) -0.52
16 GFF2583 putative lipoprotein -0.52
17 GFF4551 Putative preQ0 transporter YhhQ -0.51
18 GFF1862 Adenosine deaminase (EC 3.5.4.4) -0.50
19 GFF2792 Chaperone protein ClpB (ATP-dependent unfoldase) -0.50
20 GFF2651 Cytochrome d ubiquinol oxidase subunit X (EC 1.10.3.-) -0.48

Or look for positive cofitness