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  • Negative cofitness for GFF7306 from Variovorax sp. SCN45

    FolM Alternative dihydrofolate reductase 1
    SEED: FolM Alternative dihydrofolate reductase 1

    Computing cofitness values with 61 experiments...

    Genes with the strongest negative cofitness:

    Rank Hit Name Description Cofit  
    1 GFF4530 MBL-fold metallo-hydrolase superfamily -0.84
    2 GFF2027 2-hydroxychromene-2-carboxylate isomerase family protein -0.81
    3 GFF2575 Quinolinate synthetase (EC 2.5.1.72) -0.79
    4 GFF305 uncharacterized domain / RidA/YER057c/UK114 superfamily, group 5 -0.79
    5 GFF5410 Adenylate cyclase (EC 4.6.1.1) -0.74
    6 GFF2574 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) -0.72
    7 GFF3945 Phosphate transport regulator (distant homolog of PhoU) -0.70
    8 GFF5261 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) -0.69
    9 GFF5487 Thymidine phosphorylase (EC 2.4.2.4) -0.69
    10 GFF5870 hypothetical protein -0.68
    11 GFF6638 no description -0.68
    12 GFF3923 Kynurenine formamidase, bacterial (EC 3.5.1.9) -0.67
    13 GFF5869 internalin, putative -0.65
    14 GFF6876 Aminotransferase, DegT/DnrJ/EryC1/StrS family -0.65
    15 GFF795 5-methyltetrahydropteroyltriglutamate--homocystei ne methyltransferase (EC 2.1.1.14) -0.65
    16 GFF3497 Transcriptional regulator, Crp/Fnr family -0.64
    17 GFF5871 hypothetical protein -0.63
    18 GFF5868 hypothetical protein -0.63
    19 GFF821 Acetoacetyl-CoA reductase (EC 1.1.1.36) -0.63
    20 GFF183 Virulence protein -0.63

    Or look for positive cofitness