Negative cofitness for GFF7146 from Variovorax sp. SCN45

Putative oxidoreductase in 4-hydroxyproline catabolic gene cluster
SEED: Putative oxidoreductase in 4-hydroxyproline catabolic gene cluster

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 GFF6305 Malate synthase G (EC 2.3.3.9) -0.78
2 GFF272 thioesterase superfamily protein -0.78
3 GFF4592 Glutamate/aspartate ABC transporter, permease protein GltJ (TC 3.A.1.3.4) -0.77
4 GFF6151 Transcriptional regulator, LysR family -0.76
5 GFF401 PhbF -0.76
6 GFF2055 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) -0.76
7 GFF5676 Cytochrome O ubiquinol oxidase subunit III (EC 1.10.3.-) -0.76
8 GFF6198 D-malate dehydrogenase [decarboxylating] (EC 1.1.1.83) -0.75
9 GFF6322 Glutathione synthetase (EC 6.3.2.3) -0.75
10 GFF5331 Transposase and inactivated derivatives -0.75
11 GFF3583 AMP nucleosidase (EC 3.2.2.4) -0.75
12 GFF5823 NAD(P) transhydrogenase subunit beta (EC 1.6.1.2) -0.75
13 GFF982 Cell division protein ZapE -0.74
14 GFF6127 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit -0.74
15 GFF2818 Phosphoenolpyruvate synthase (EC 2.7.9.2) -0.74
16 GFF6194 ABC transporter, ATP-binding protein (cluster 5, nickel/peptides/opines) -0.74
17 GFF1900 Transcriptional regulator, LysR family -0.74
18 GFF6191 Aldehyde dehydrogenase (EC 1.2.1.3) -0.74
19 GFF5678 Cytochrome O ubiquinol oxidase subunit II (EC 1.10.3.-) -0.74
20 GFF1127 Aldehyde dehydrogenase (EC 1.2.1.3) -0.73

Or look for positive cofitness