Negative cofitness for GFF6658 from Variovorax sp. SCN45

Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtC (RND type)
SEED: Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA
KEGG: RND superfamily, multidrug transport protein MdtC

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	GFF3710		Lactoylglutathione lyase and related lyases	-0.60
2	GFF3061		BUG/TctC family periplasmic protein	-0.58
3	GFF2105		3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9)	-0.57
4	GFF2995		hypothetical protein	-0.56
5	GFF4615		5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase	-0.55
6	GFF3754		Fumarylacetoacetate hydrolase family protein	-0.54
7	GFF3499		Toxin HigB / Protein kinase domain of HipA	-0.54
8	GFF4858		Transposase	-0.54
9	GFF3489		Transcriptional regulator, AcrR family	-0.54
10	GFF5412		no description	-0.53
11	GFF3964		2-hydroxymuconic semialdehyde hydrolase (EC 3.7.1.9)	-0.52
12	GFF2605		Tricarboxylate transport sensor protein TctE	-0.52
13	GFF5994		Chlorogenate esterase	-0.52
14	GFF728		putative 2-pyrone-4,6-dicarboxylic acid hydrolase	-0.51
15	GFF3810		Conserved membrane protein in copper uptake, YcnI / Copper metallochaperone PCu(A)C, inserts Cu(I) into cytochrome oxidase subunit II	-0.50
16	GFF3801		Response regulator receiver protein	-0.50
17	GFF4008		Transcriptional regulator, LysR family	-0.50
18	GFF4298		2-hydroxycyclohexanecarboxyl-CoA dehydrogenase	-0.50
19	GFF3068		FIG00538108: hypothetical protein	-0.49
20	GFF2686		Large protein containing transglutaminase-like domain	-0.49

Or look for positive cofitness