Negative cofitness for GFF6538 from Variovorax sp. SCN45

Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
SEED: Acetoacetyl-CoA synthetase (EC 6.2.1.16) / Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 GFF6636 Hydrolase, alpha/beta fold family -0.47
2 GFF7212 Nitrilotriacetate monooxygenase [FMNH2] -0.44
3 GFF1021 Transcriptional regulator, Xre-family with cupin domain -0.44
4 GFF6455 Bll3817 protein -0.43
5 GFF2565 Two-component transcriptional response regulator receiver domain -0.43
6 GFF6120 Exonuclease SbcC -0.42
7 GFF2685 DNA internalization-related competence protein ComEC/Rec2 -0.41
8 GFF4612 Short-chain dehydrogenase/reductase SDR -0.41
9 GFF3969 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; Vanillate O-demethylase oxidoreductase (EC 1.14.13.-) -0.40
10 GFF2336 Transcriptional regulator, AraC family -0.39
11 GFF2106 hypothetical protein -0.39
12 GFF191 (Y14336) putative extracellular protein containing predicted 35aa signal peptide -0.39
13 GFF744 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases -0.39
14 GFF1091 Exopolyphosphatase (EC 3.6.1.11) -0.38
15 GFF3557 hypothetical protein -0.38
16 GFF4718 ABC transporter, ATP-binding protein (cluster 3, basic aa/glutamine/opines) -0.38
17 GFF6083 hypothetical protein PA3071 -0.38
18 GFF45 Phospholipase C (EC 3.1.4.3) -0.38
19 GFF4568 Enoyl-CoA hydratase (EC 4.2.1.17) / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase (EC 5.3.3.8) / 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl-CoA epimerase (EC 5.1.2.3) -0.38
20 GFF1597 Acetolactate synthase large subunit (EC 2.2.1.6) -0.37

Or look for positive cofitness