Negative cofitness for GFF6198 from Variovorax sp. SCN45

D-malate dehydrogenase [decarboxylating] (EC 1.1.1.83)
SEED: Tartrate dehydrogenase (EC 1.1.1.93) @ Tartrate decarboxylase (EC 4.1.1.73) @ D-malic enzyme (EC 1.1.1.83)
KEGG: tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 GFF6424 Phosphoenolpyruvate carboxykinase [GTP] (EC 4.1.1.32) -0.87
2 GFF2683 Protein containing domains DUF404, DUF407 -0.82
3 GFF4397 hypothetical protein -0.82
4 GFF7375 Arginine:pyruvate transaminase -0.82
5 GFF255 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase (EC 2.3.1.117) -0.81
6 GFF5307 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.241) -0.80
7 GFF6042 Fatty acid desaturase (EC 1.14.19.1); Delta-9 fatty acid desaturase (EC 1.14.19.1) -0.80
8 GFF5402 Transcriptional regulator, IclR family -0.79
9 GFF3923 Kynurenine formamidase, bacterial (EC 3.5.1.9) -0.78
10 GFF6278 Ferredoxin-dependent glutamate synthase (EC 1.4.7.1) -0.78
11 GFF7374 FIG00984748: hypothetical protein -0.76
12 GFF7295 HPr kinase/phosphorylase -0.75
13 GFF7322 hypothetical protein -0.75
14 GFF7146 Putative oxidoreductase in 4-hydroxyproline catabolic gene cluster -0.75
15 GFF5487 Thymidine phosphorylase (EC 2.4.2.4) -0.75
16 GFF3582 Tripartite tricarboxylate transporter TctC family -0.74
17 GFF7371 Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5) -0.74
18 GFF4373 FIG131328: Predicted ATP-dependent endonuclease of the OLD family -0.74
19 GFF5668 Uncharacterized MFS-type transporter -0.74
20 GFF7373 CaiB/BaiF family protein -0.74

Or look for positive cofitness