Negative cofitness for GFF6002 from Variovorax sp. SCN45

DNA topoisomerase IB (poxvirus type) (EC 5.99.1.2)
SEED: DNA topoisomerase IB (poxvirus type) (EC 5.99.1.2)
KEGG: DNA topoisomerase I

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	GFF5673		Sensor histidine kinase PrrB (RegB) (EC 2.7.3.-)	-0.59
2	GFF2281		Short-chain dehydrogenase/reductase SDR	-0.57
3	GFF1700		hypothetical protein	-0.56
4	GFF7289		5'-methylthioadenosine nucleosidase (EC 3.2.2.16) @ S-adenosylhomocysteine nucleosidase (EC 3.2.2.9)	-0.56
5	GFF6033		Branched-chain amino acid ABC transporter, permease protein LivH (TC 3.A.1.4.1)	-0.54
6	GFF1012		Cystathionine beta-lyase (EC 4.4.1.8)	-0.54
7	GFF7093		5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-)	-0.53
8	GFF4968		Succinate dehydrogenase/fumarate reductase, flavoprotein subunit	-0.53
9	GFF1002		HflK protein	-0.53
10	GFF6514		Short-chain dehydrogenase	-0.53
11	GFF1651		Transcriptional regulator, AcrR family	-0.52
12	GFF559		FIG016425: Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)	-0.52
13	GFF1738		Uncharacterized proteins YbdD and YjiX	-0.51
14	GFF219		GTP-binding protein TypA/BipA	-0.51
15	GFF237		ABC-type branched-chain amino acid transport systems, periplasmic component	-0.51
16	GFF495		Kup system potassium uptake protein	-0.51
17	GFF5689		Oxidoreductase, 2OG-Fe(II) oxygenase family	-0.50
18	GFF3999		GMP reductase (EC 1.7.1.7)	-0.50
19	GFF122		Dihydroorotate dehydrogenase electron transfer subunit (EC 1.3.3.1)	-0.50
20	GFF2023		Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)	-0.50

Or look for positive cofitness