Negative cofitness for GFF5813 from Variovorax sp. SCN45

Heavy metal sensor histidine kinase
SEED: Signal transduction histidine kinase
KEGG: two-component system, OmpR family, heavy metal sensor histidine kinase CusS

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 GFF2338 Amidase family protein Atu4441 -0.58
2 GFF6160 Dehydrogenase molybdenum cofactor insertion protein, XdhC/CoxF family -0.57
3 GFF6861 no description -0.56
4 GFF4718 ABC transporter, ATP-binding protein (cluster 3, basic aa/glutamine/opines) -0.55
5 GFF2811 Transcriptional regulator, YafY family -0.54
6 GFF3555 Mg-chelatase subunit ChlD -0.54
7 GFF6950 Acetoacetyl-CoA reductase (EC 1.1.1.36) -0.54
8 GFF508 ABC transporter, permease protein 2 (cluster 4, leucine/isoleucine/valine/benzoate) -0.54
9 GFF5519 Transcriptional regulator -0.52
10 GFF2922 Oxidoreductase, short-chain dehydrogenase/reductase family -0.52
11 GFF7325 Glucans biosynthesis glucosyltransferase H -0.51
12 GFF5094 BUG/TctC family periplasmic protein -0.51
13 GFF1014 Arylesterase precursor (EC 3.1.1.2) -0.50
14 GFF6201 Oxidoreductase, aldo/keto reductase family -0.50
15 GFF3258 hypothetical protein -0.49
16 GFF6491 SAM-dependent methyltransferase -0.49
17 GFF4427 hypothetical protein -0.49
18 GFF6635 FIG00441227: hypothetical protein -0.49
19 GFF5233 General secretion pathway protein F / Type II secretory pathway, component PulF -0.49
20 GFF4582 TRAP-type C4-dicarboxylate transport system, small permease component -0.48

Or look for positive cofitness