Negative cofitness for GFF5461 from Variovorax sp. SCN45

2-dehydrotetronate isomerase (EC 5.3.1.35)
SEED: Hydroxypyruvate isomerase (EC 5.3.1.22)
KEGG: hydroxypyruvate isomerase

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 GFF397 NAD(P)H-hydrate epimerase (EC 5.1.99.6) / ADP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.136) -0.58
2 GFF7269 Altronate dehydratase (EC 4.2.1.7) -0.57
3 GFF5238 General secretion pathway protein L -0.57
4 GFF4404 Mobile element protein -0.52
5 GFF1274 Glutamate racemase (EC 5.1.1.3) -0.51
6 GFF4321 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) -0.51
7 GFF6472 membrane efflux protein -0.50
8 GFF5217 Ferric iron ABC transporter, iron-binding protein -0.50
9 GFF2655 Efflux ABC transporter for glutathione/L-cysteine, essential for assembly of bd-type respiratory oxidases => CydD subunit -0.50
10 GFF6115 ABC transporter, substrate-binding protein (cluster 5, nickel/peptides/opines) -0.49
11 GFF3373 Hydroxymethylglutaryl-CoA reductase (EC 1.1.1.34) -0.49
12 GFF7280 no description -0.49
13 GFF876 hypothetical protein -0.48
14 GFF4351 Branched-chain amino acid ABC transporter, amino acid-binding protein (TC 3.A.1.4.1) -0.48
15 GFF1111 probable membrane protein NMA1176 -0.46
16 GFF65 hypothetical protein -0.46
17 GFF6366 T6SS component TssG (ImpH/VasB) -0.46
18 GFF6566 hypothetical protein -0.45
19 GFF5469 Hydroxymethylpyrimidine ABC transporter, transmembrane component -0.45
20 GFF5135 DNA repair exonuclease family protein YhaO -0.45

Or look for positive cofitness