Negative cofitness for GFF487 from Sphingobium sp. HT1-2

Pyruvate kinase (EC 2.7.1.40)
SEED: Pyruvate kinase (EC 2.7.1.40)
KEGG: pyruvate kinase

Computing cofitness values with 18 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 GFF3277 IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) -0.76
2 GFF818 Phosphoserine aminotransferase (EC 2.6.1.52) -0.75
3 GFF2554 hypothetical protein -0.75
4 GFF3061 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (EC 5.3.1.16) -0.74
5 GFF4294 DNA-binding protein HU-beta -0.74
6 GFF367 Leucyl/phenylalanyl-tRNA--protein transferase (EC 2.3.2.6) -0.74
7 GFF1592 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) -0.74
8 GFF825 L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) -0.73
9 GFF13 hypothetical protein -0.73
10 GFF4746 3-hydroxyacyl-CoA dehydrogenase [fadN-fadA-fadE operon] (EC 1.1.1.35) / Enoyl-CoA hydratase [fadN-fadA-fadE operon] (EC 4.2.1.17) -0.72
11 GFF4964 Hydrolase, alpha/beta fold family -0.72
12 GFF3336 Aerobic cobaltochelatase CobT subunit (EC 6.6.1.2) -0.72
13 GFF1759 alpha-galactosidase (EC 3.2.1.22) -0.71
14 GFF4309 hypothetical protein -0.71
15 GFF215 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13), C-terminal domain -0.71
16 GFF2662 hypothetical protein -0.71
17 GFF736 hypothetical protein -0.70
18 GFF216 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13), N-terminal domain -0.70
19 GFF3988 hypothetical protein -0.70
20 GFF1490 Threonine dehydratase, catabolic (EC 4.3.1.19) @ L-serine dehydratase, (PLP)-dependent (EC 4.3.1.17) -0.70

Or look for positive cofitness