Negative cofitness for GFF4851 from Variovorax sp. SCN45

Coupling protein VirD4, ATPase required for T-DNA transfer
SEED: Type IV secretion system protein VirD4
KEGG: type IV secretion system protein VirD4

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	GFF6230		Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-0.71
2	GFF5409		FIG00576366: hypothetical protein	-0.70
3	GFF6635		FIG00441227: hypothetical protein	-0.69
4	GFF5410		Adenylate cyclase (EC 4.6.1.1)	-0.68
5	GFF4807		Uncharacterized GST-like protein yncG	-0.67
6	GFF5487		Thymidine phosphorylase (EC 2.4.2.4)	-0.67
7	GFF3582		Tripartite tricarboxylate transporter TctC family	-0.66
8	GFF2682		Protein containing domains DUF403	-0.65
9	GFF183		Virulence protein	-0.63
10	GFF6042		Fatty acid desaturase (EC 1.14.19.1); Delta-9 fatty acid desaturase (EC 1.14.19.1)	-0.62
11	GFF1268		FIG022199: FAD-binding protein	-0.62
12	GFF7371		Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5)	-0.61
13	GFF7375		Arginine:pyruvate transaminase	-0.61
14	GFF5870		hypothetical protein	-0.61
15	GFF5307		Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.241)	-0.61
16	GFF5325		3-dehydroquinate synthase (EC 4.2.3.4)	-0.61
17	GFF1760		Probable transmembrane protein	-0.61
18	GFF6209		ABC transporter, ATP-binding protein (cluster 3, basic aa/glutamine/opines)	-0.60
19	GFF5064		Exonuclease SbcC	-0.60
20	GFF3945		Phosphate transport regulator (distant homolog of PhoU)	-0.60

Or look for positive cofitness