Negative cofitness for GFF4822 from Variovorax sp. SCN45

Thiamine pyrophosphate-requiring enzymes
SEED: Acetolactate synthase large subunit (EC 2.2.1.6)
KEGG: acetolactate synthase I/II/III large subunit

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	GFF5903		Iron-sulfur cluster regulator IscR	-0.61
2	GFF7067		Oxidoreductase, short-chain dehydrogenase/reductase family	-0.61
3	GFF66		hypothetical protein	-0.58
4	GFF147		Transcriptional regulator	-0.57
5	GFF3701		FIG004694: Hypothetical protein	-0.56
6	GFF39		Transcriptional regulator, LysR family	-0.55
7	GFF6015		Transcriptional regulator PA0877, LysR family	-0.54
8	GFF6385		Mll4878 protein	-0.53
9	GFF2781		Phosphopantetheine-binding	-0.53
10	GFF5582		BUG/TctC family periplasmic protein	-0.53
11	GFF4569		3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9)	-0.53
12	GFF1317		no description	-0.51
13	GFF1599		Branched-chain amino acid transport system permease protein LivM (TC 3.A.1.4.1)	-0.50
14	GFF870		TonB-dependent receptor	-0.50
15	GFF3526		hypothetical protein	-0.50
16	GFF313		FIG027190: Putative transmembrane protein	-0.50
17	GFF1349		Thioesterase	-0.50
18	GFF4628		hypothetical protein	-0.50
19	GFF6218		no description	-0.49
20	GFF2382		Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific) (EC 3.6.1.66)	-0.49

Or look for positive cofitness