Negative cofitness for PS417_24545 from Pseudomonas simiae WCS417

isomerase
SEED: Hydroxypyruvate isomerase (EC 5.3.1.22)

Computing cofitness values with 552 experiments...

Genes with the strongest negative cofitness:

Rank	Hit	Name	Description	Cofit
1	PS417_01565		imidazole glycerol phosphate synthase	-0.27
2	PS417_04420		histidinol dehydrogenase	-0.26
3	PS417_23810		acetolactate synthase 3 catalytic subunit	-0.25
4	PS417_12290		sulfite reductase	-0.25
5	PS417_18530		O-succinylhomoserine sulfhydrylase	-0.25
6	PS417_04415		ATP phosphoribosyltransferase (EC 2.4.2.17) (from data)	-0.25
7	PS417_02510		ATP phosphoribosyltransferase regulatory subunit	-0.25
8	PS417_26745		methionine biosynthesis protein MetW	-0.25
9	PS417_16465		sirohydrochlorin ferrochelatase	-0.25
10	PS417_20160		cysteine synthase	-0.25
11	PS417_18560		N-(5'-phosphoribosyl)anthranilate isomerase	-0.24
12	PS417_01850		phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data)	-0.24
13	PS417_23800		ketol-acid reductoisomerase	-0.24
14	PS417_01575		1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data)	-0.24
15	PS417_23805		acetolactate synthase 3 regulatory subunit	-0.24
16	PS417_00185		tryptophan synthase subunit beta	-0.24
17	PS417_26890		dihydroxy-acid dehydratase	-0.24
18	PS417_25725		anthranilate synthase component I	-0.24
19	PS417_25715		anthranilate phosphoribosyltransferase	-0.23
20	PS417_27195		N-acetylglutamate synthase	-0.23

Or look for positive cofitness