Negative cofitness for GFF4772 from Variovorax sp. SCN45

D-mannose isomerase (EC 5.3.1.7)
SEED: D-mannose isomerase (EC 5.3.1.7)

Computing cofitness values with 61 experiments...

Genes with the strongest negative cofitness:

Rank Hit Name Description Cofit  
1 GFF3592 hypothetical protein -0.61
2 GFF7094 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) -0.60
3 GFF3525 Protein tyrosine/serine phosphatase -0.59
4 GFF5889 Uracil-DNA glycosylase, family 1 (EC 3.2.2.27) -0.58
5 GFF2000 Phosphomethylpyrimidine synthase ThiC (EC 4.1.99.17) -0.57
6 GFF1517 TRAP-type transport system, small permease component, predicted N-acetylneuraminate transporter -0.57
7 GFF5465 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1; Vanillate O-demethylase oxidoreductase (EC 1.14.13.-) -0.57
8 GFF3496 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3) -0.57
9 GFF2253 no description -0.56
10 GFF4189 NUDIX hydrolase -0.54
11 GFF1683 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) -0.54
12 GFF3081 no description -0.54
13 GFF4134 Small molecule metabolism -0.53
14 GFF357 SOS-response repressor and protease LexA (EC 3.4.21.88) -0.53
15 GFF1187 Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) -0.53
16 GFF6928 Putative transmembrane protein -0.52
17 GFF1190 Glycine oxidase ThiO (EC 1.4.3.19) -0.52
18 GFF5272 Various polyols ABC transporter, substrate-binding protein -0.52
19 GFF4383 hypothetical protein -0.52
20 GFF1755 diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) -0.52

Or look for positive cofitness